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Most often these types of symptoms are more likely to be caused by benign (non-cancer) conditions, like hemorrhoids, anal fissures, or anal warts. Still, if you have any of these symptoms, its important to have them checked by a doctor so that the cause can be found and treated, if needed. Anal cancer is an uncommon malignancy that starts in the anus-- the opening at the end of the rectum. The american society of clinical oncology estimates that 8,300 cases of anal cancer will be. A biopsy is the only way to know for sure if you have cancer. For anal cancer, a biopsy is most often done during an endoscopy. If the tumor is very small and is only on the lining of the anus, the doctor may be able to take out all of the tumor during the biopsy. Anal cancer symptoms five signs of the deadly disease you need to know anal cancer is a rare form of the disease that affects the end of the bowel. If these tests suggest you have anal cancer, you may have some scans to check whether the cancer has spread. Once these are complete, your doctors will be able to stage the cancer. This means giving it a score to describe how large it is and how far its spread. You can read more about the stages of anal cancer on the cancer research uk website. now before you bolt from this page to go stick your head in the sand somewhere, know that, mostly, if you do have one or more of these symptoms,. How do i know if i have anal cancer? What signs or symptoms may make you suspect you may have anal cancer. anal cancer is rare and more likely to affect women than men. About 25 percent of people diagnosed with anal cancer never experience any symptoms, while others experience a variety. In some cases, symptoms do not appear until the cancer has spread.