Fibrotic anal tissue

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Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodelling and the formation of permanent scar tissue.   the term fibrosis describes the development of fibrous connective tissue as a reparative response to injury or damage. Fuzheng huayu recipe (fzhy) is a herbal product for the treatment of liver fibrosis approved by the chinese state food and drug administration (sfda), but its pharmacokinetics and tissue distribution had not been investigated. Anal papillae,1 which are also called as anal fibroma, papillitis hypertrophicans,. Fibrotic proliferation within the range of the linea dentata, the ano rectal zone and the distal rectal. Fibrotic connective tissue in parts, with increase in capillary contents. Comparative pharmacokinetic and tissue distribution profiles of four major bioactive components in normal and hepatic fibrosis rats after oral administration of fuzheng huayu recipe. Deep fibrotic nodular endometriosis involving the cul-de-sac requires the excision of white fibronodular tissue from the uterosacral ligaments, posterior cervix, posterior vagina, and anterior rectum. Less commonly, the sigmoid colon, its mesocolon, and the lateral rectum are involved (reich et al,1991,a).

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