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The word lesion sometimes brings to mind something like a sore, but anal lesions are often simply abnormalities that can be seen on the surface of the skin of the anus. Anal cancer this page is intended to provide information about anal cancer and its precursors, high grade and low grade anal squamous intraepithelial lesions (hsil and lsil respectively). female genital sores are bumps and lesions in or around the vagina. See detailed information below for a list of 24 causes of perianal lesions, symptom checker, including diseases and drug side effect causes. Review causes of perianal lesions causes symptom checker home diagnostic testing and perianal lesions. The clinical effectiveness and cost-effectiveness of screening for anal squamous intraepithelial lesions in homosexual and bisexual hiv-positive men. The answer is e perianal crohns disease manifested as anal fissures and elephant ear skin tags. Crohns disease is a chronic, transmural disease that can affect any part of the. skin lesions can be inherited or caused by inflammation, injury,.